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Encompassing Amino Acids: 29-216
Applications: Useful for studying protein binding and screening small molecular inhibitors
Description: Human secreted OX40, Fc fusion protein,also known as Tumor Necrosis FactorReceptor Superfamily Member 4,TNFRSF4, and CD134, GenBankAccession No. NM_003327, a.a. 29-216expressed in a HEK293 cell expressionsystem. MW = 46.8 kDa (monomer). Thisprotein runs at a higher MW by SDS-PAGEdue to glycosylation.
Endotoxin Level: <1 EU/µg
Format: Aqueous buffer solution.
Formulation: 40 mM Tris-HCl, pH 8.0, 110 mM NaCl, 2.2 mM KCl, and 20% glycerol
Genbank: NM_003327
Storage Stability: At least 6 months at -80°C.
Tags: C-terminal Fc fusion (Human IgG1)
Uniprot: P43489
Warnings: Avoid freeze/thaw cycles. Protein may be diluted to ≥100 µg/ml in PBS + glycerol and stored at -80°C.
Biosafety Level: Not applicable (BSL-1)
References: 1. Rogers, P.R. et al., Immunity. 2001; 15(3): 445-455.
2. Ito, T. et al., J. Exp. Med. 2005; 202(9): 1213-1223.