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Applications: Useful for the study of protein-protein interaction and in vitro and in vivo protein function studies.
Description: Mouse secreted Programmed Cell Death 1 (PD-1)-Fc fusion protein, also known as CD279, PDCD1, and SLEB2, GenBank Accession No. NM_008798, a.a. 25-167, fused at the C-terminus to the Fc portion of mouse IgG2a, expressed in a HEK293 cell expression system. MW = 43.2 kDa. Note: this protein runs at an apparent higher molecular weight due to glycosylation.
Format: Aqueous buffer solution.
Formulation: 8 mM phosphate, pH 7.4, 110 mM NaCl, 2.2 mM KCl, pH 7.4, and 20% glycerol
Genbank: NM_008798
Host Cell Line: HEK293
Storage Stability: At least 6 months at -80°C.
Tags: C-terminal Fc fusion (Mouse IgG2a)
Uniprot: Q02242
Warnings: Avoid freeze/thaw cycles. Protein may be diluted to ≥100 µg/ml in PBS + glycerol and stored at -80°C.
Biosafety Level: Not applicable (BSL-1)
References: 1. Agata, Y., et al., Int. Immunol. 1996; 8(5): 765-772.
2. Freeman, G.J., et al., J. Exp. Med. 2000; 192(7): 1027-1034.