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Encompassing Amino Acids: 25-172
Description: Woodchuck (Groundhog, Marmota monax) secreted programmed cell death 1 (PD-1) also known as, PDCD1, SLEB2, CD279 and HPD-L, GenBank Accession No. HQ403652.1, a.a 25-172, fused at the C-terminus to the Fc portion of Human IgG1, expressed in a HEK293 cell expression system. MW = 43 kDa. This protein runs at a higher M.W. by SDS-PAGE due to glycosylation.
Format: Aqueous buffer solution.
Formulation: 8 mM Phosphate, pH 7.4, 400 mM NaCl, 2.2 mM KCl, and 20% glycerol.
Genbank: HQ403652.1
Storage Stability: At least 6 months at -80°C. Avoid freeze/thaw cycles. Protein may be diluted to ≥100 µg/ml in PBS + glycerol and stored at -80°C.
Tags: C-terminal Fc-Fusion
Biosafety Level: Not applicable (BSL-1)
References: 1.Shinohara, T., et al., Genomics. 1994 Oct;23(3):704-6.2.James, E.S., et al., Genes Immun. 2005 Aug;6(5):430-7.