Products from BPS Bioscience require a minimum order value above 400€
Encompassing Amino Acids: 20-219
Applications: Useful for the study of protein-protein interaction and in vitro and in vivo protein function.
Assay Conditions: PD-1-PD-L2 binding activity, measuredusing the using the PD-1:PDL2[Biotinylated] Inhibitor Screening AssayKit, BPS Bioscience, Catalog #72004.
Description: Human secreted Programmed Death Ligand 2 (PD-L2)-Fc fusion protein, also known as CD273, PDCDL1G2, and B7-DC, GenBank Accession No. NM_025239, a.a. 20-219, fused at the C-terminus to the Fc portion of human IgG1, with C-terminal Avitag ™ expressed in a HEK293 cell expression system and enzymatically biotinlabeled using Avi-tag™ technology. MW = 51 kDa.
Format: Aqueous buffer solution
Formulation: 8 mM phosphate, pH 7.4, 110 mM NaCl, 2.2 mM KCl, pH 7.4, and 20% glycerol
Genbank: NM_025239
Storage Stability: At least 6 months at -80°C.
Tags: C-terminal Fc fusion (Human IgG1), C-terminal Avi-tag™
Uniprot: Q9BQ51
Warnings: Avoid freeze/thaw cycles. Protein may be diluted to ≥100 µg/ml in PBS + glycerol and stored at -80°C.
Biosafety Level: Not applicable (BSL-1)
References: 1. Latchman, Y., et al., Nat. Immunol. 2001 Mar;2(3):261-8.
2. Saunders, P.A., et al., Eur. J. Immunol. 2005 Dec;35(12):3561-9.