PE/Cyanine7 Anti-Mouse CD45R/B220 Antibody(RA3.3A 1/6.1), PE/Cy7, Rat, Monoclonal

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Background: CD45R, also known as B220, is an isoform of CD45. It is a member of the protein tyrosine phosphatase (PTP) family with a molecular weight of approximately 180-240 kD. CD45R is expressed on B cells (at all developmental stages from pro-B cells through mature B cells), activated B cells, and subsets of T and NK cells. CD45R (B220) is also expressed on a subset of abnormal T cells involved in the pathogenesis of systemic autoimmunity in MRL-Fas^lpr and MRL-Fas^gld mice. It plays a critical role in TCR and BCR signaling. The primary ligands for CD45 are galectin-1, CD2, CD3, and CD4. CD45R is commonly used as a pan-B cell marker; however, CD19 may be more appropriate for B cell specificity.

Abbre: Mouse CD45R/B220.

Buffer: PBS with 0.05% Proclin300, 1% BSA.

Clone No: RA3.3A 1/6.1.

Conjugation: PE/Cyanine7.

• SKU: ELSE-AB-F1112H-200
• Manufacturer: Elabscience Biotechnology
• Manufacturer SKU: ELA-E-AB-F1112H-100X2
• Package Unit: 100x2 Tests
• Quantity Unit: PAK
• Reactivity: Mouse (Murine)
• Clonality: Monoclonal
• Application: Flow Cytometry
• Isotype: Rat IgM κ
• Human Gene ID: 19264
• Host: Rat