PE/Elab Fluor 594 Anti-Human CD86 Antibody(BU63), Mouse, Monoclonal

Swissprot: P42081.

Background: CD86 is an 80 kD immunoglobulin superfamily member also known as B7-2, B70, and Ly-58. CD86 is expressed on activated B and T cells, monocytes/macrophages, dendritic cells, and astrocytes. CD86, along with CD80, is the ligand of CD28 and CD152 (CTLA-4). CD86 is expressed earlier in the immune response than CD80. CD86 has also been shown to be involved in immunoglobulin class-switching and triggering of NK cell-mediated cytotoxicity. CD86 binds to CD28 to transduce costimulatory signals for T cell activation, proliferation, and cytokine production. CD86 can bind to CD152 as well, also known as CTLA-4, to deliver an inhibitory signal to T cells.

Abbre: Human CD86.

Buffer: PBS with 0.05% Proclin300, 1% BSA.

Clone No: BU63.

Conjugation: PE/Elab Fluor® 594.

• SKU: ELSE-AB-F1012P-20
• Manufacturer: Elabscience Biotechnology
• Manufacturer SKU: ELA-E-AB-F1012P-20
• Package Unit: 20 Tests
• Quantity Unit: PAK
• Reactivity: Human
• Clonality: Monoclonal
• Application: Flow Cytometry
• Human Gene ID: 942
• Host: Mouse