Conjugation: HRP: Horseradish Peroxidase
Description of Target: The protein encoded by this gene belongs to a family of bifunctional proteins that are involved in both the synthesis and degradation of fructose-2,6-bisphosphate, a regulatory molecule that controls glycolysis in eukaryotes. The encoded protein has a 6-phosphofructo-2-kinase activity that catalyzes the synthesis of fructose-2,6-bisphosphate (F2,6BP), and a fructose-2,6-biphosphatase activity that catalyzes the degradation of F2,6BP. This protein is required for cell cycle progression and prevention of apoptosis. It functions as a regulator of cyclin-dependent kinase 1, linking glucose metabolism to cell proliferation and survival in tumor cells. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human F263
Molecular Weight: 57kDa
Peptide Sequence: Synthetic peptide located within the following region:
VESVCTHRERSEDAKKGPNPLMRRNSVTPLASPEPTKKPRINSFEEHVASProduct Format: Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.
Protein Name: 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3
Protein Size: 520
Purification: Affinity Purified