PKR (phospho Thr446) antibody (HL1439)

Clone Name: HL1439

Light Chain: Kappa

Application Note: WB: 1:500-1:3000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Calculated MW: 62

Form: Liquid

Buffer (with preservative): PBS, no preservative.

Concentration: 1 mg/ml (Please refer to the vial label for the specific concentration.)

Background: The protein encoded by this gene is a serine/threonine protein kinase that is activated by autophosphorylation after binding to dsRNA. The activated form of the encoded protein can phosphorylate translation initiation factor EIF2S1, which in turn inhibits protein synthesis. This protein is also activated by manganese ions and heparin. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]

Uniprot ID: P19525

Antigen Species: Human

Immunogen: Carrier-protein conjugated synthetic peptide surrounding phospho Thr446 of human PKR. The exact sequence is proprietary.

Purification: Affinity purified by Protein A.

Conjugation: Unconjugated

Full Name: eukaryotic translation initiation factor 2 alpha kinase 2

• SKU: GTX636912-S-25
• Manufacturer: GeneTex
• Manufacturer SKU: GTX636912-S-25
• Green Labware: No
• Package Unit: 25 μl
• Quantity Unit: STK
• Reactivity: Human
• Clonality: Monoclonal
• Application: Immunofluorescence, Western Blotting, Immunocytochemistry
• Isotype: IgG
• Human Gene ID: 5610
• Host: Rabbit