Abbreviation: Placental alkaline phosphatase (PLAP)
Target Synonym: ALPP; ALP; PALP; PLAP; PLAP-1; alkaline phosphatase; placental
Conjugation: Unconjugated
UNIProt ID: P05187
Background: The protein encoded by this gene is an alkaline phosphatase, a metalloenzyme that catalyzes the hydrolysis of phosphoric acid monoesters. It belongs to a multigene family composed of four alkaline phosphatase isoenzymes. The enzyme functions as a homodimer and has a catalytic site containing one magnesium and two zinc ions, which are required for its enzymatic function. The protein is primarily expressed in placental and endometrial tissue; however, strong ectopic expression has been detected in ovarian adenocarcinoma, serous cystadenocarcinoma, and other ovarian cancer cells.
Concentration: 1mg/mL
Immunogen: Recombinant fusion protein of human Placental alkaline phosphatase
Dilution: WB 1:500-1:2000,IP 50-1:200