Abbreviation: PLP1
Target Synonym: PLP1;GPM6C;HLD1;MMPL;PLP;PLP/DM20;PMD;SPG2
Conjugation: Unconjugated
UNIProt ID: P60201
Background: This gene encodes a transmembrane proteolipid protein that is the predominant component of myelin. The encoded protein may play a role in the compaction, stabilization, and maintenance of myelin sheaths, as well as in oligodendrocyte development and axonal survival. Mutations in this gene cause Pelizaeus-Merzbacher disease and spastic paraplegia type 2. Alternatively splicing results in multiple transcript variants, including the DM20 splice variant.
Concentration: 1mg/mL
Immunogen: Recombinant fusion protein of human PLP1
Dilution: WB 1:500-1:2000,IHC 1:50-1:200,IF 1:50-1:200