Immunogen: Unknown or proprietery to MONOSAN and/or its suppliers
Concentration: n/a
Storage buffer: Tris Buffer, pH 7.3-7.7, containing 1% BSA and <0.1% Sodium Azide
Additional info: Anti-Glucagon antibody detects glucagon-secreting cells and tumors such as glucagonomas. Studies show that approximately 80% of glucagonomas are malignant and these patients have a syndrome often initially recognized by dermatologists. Symptoms include necrolytic migratory erythema as well as diabetes, anemia, stomatitis, weight loss, frequent venous thromboses, and in some instances, diarrhea and psychiatric disturbances. The diagnosis may be readily confirmed by the demonstration of elevated plasma glucagon concentration.
References: Quesada I, et al. J Endocrinol. 2008; 199:5-19/Gurlo T, et al. J Histotechnol. 2016; 39:8-16/Wewer Albrechtsen NJ, et al. Biomark Med. 2016; 10:1141-51
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