Polyclonal antibody against Granzyme B

Immunogen: Unknown or proprietery to MONOSAN and/or its suppliers

Concentration: n/a

Storage buffer: Tris Buffer, pH 7.3-7.7, containing 1% BSA and <0.1% Sodium Azide

Additional info: Granzymes are serine proteases which are stored in specialized lytic granules of cytotoxic T lymphocytes and in natural killer cells. Anti-Granzyme B has been useful in diagnosing Natural killer/T cell lymphoma, as well as anaplastic large cell lymphoma. High percentages of cytotoxic T cells have been shown to be an unfavorable prognostic indicator in Hodgkin’s disease.

References: Kummer JA, et al. Clin Exp Immunol. 1995; 100:164-72/Oudejans JJ, et al. Am J Pathol. 1996; 148:233-40/Oudejans JJ, et al. Blood. 1997; 89:1376-82

• SKU: SANPS318
• Manufacturer: Sanbio / Monosan
• Manufacturer SKU: PS318
• Package Unit: 1 ml
• Quantity Unit: STK
• Reactivity: Human
• Clonality: Polyclonal
• Application: Immunohistochemistry (paraffin)
• Host: Rabbit
• Conjugate: Unconjugated