Polyclonal Guinea-Pig anti-CGRP

Immunogen: Synthetic human calcitonin gene-related peptide (CGRP; #6009, Peninsula)

Concentration: n/a

Storage buffer: Lyophilized; reconstitute in 100 µl dist. water

Additional info: The CGRP-sequence was predicted from the corresponding mRNA. CGRP is present in the C-cells of the thyroid and in nerves, in both brain and periphery, particularly within the sensory system. CGRP is a potent vasodilator, probably involved in neurogenic inflammation. Medullary carcinomas of the thyroid contain large amounts of CGRP. Absorption with 10-100 ug CGRP per ml diluted antiserum abolishes the staining while calcitonin, does not. Cross-reacts with amylin (IAPP).
Positive control: Stefanini-fixed frozen sections of rat colon.

References: Ekblad, E. et al. Neuroscience 1988;27:655–74 /Persson, K et al. Neuroscience 1997; 77:271–81

• SKU: SANPS252
• Manufacturer: Sanbio / Monosan
• Manufacturer SKU: PS252
• Package Unit: 50 µl
• Quantity Unit: STK
• Reactivity: Human, Rat (Rattus)
• Clonality: Polyclonal
• Application: Immunofluorescence, Immunohistochemistry (frozen), Immunohistochemistry (paraffin)
• Host: Other
• Conjugate: Unconjugated