Immunogen: Calcitonin gene-related peptide (synthetic, rat, (#6006, Peninsula), conjugated to BSA
Concentration: n/a
Storage buffer: Lyophilized; reconstitute in 100 µl dist. water
Additional info: The CGRP-sequence was predicted from the corresponding mRNA. CGRP is present in the C-cells of the thyroid and in nerves, in both brain and periphery, particularly within the sensory system. CGRP is a potent vasodilator, probably involved in neurogenic inflammation. Medullary carcinomas of the thyroid contain large amounts of CGRP. Absorption with 10-100 ug CGRP per ml diluted antiserum abolishes the staining while calcitonin does not. Does not cross-react with amylin (IAPP).
Positive control: frozen sections of rat colon.
References: Schulze, E. et al. Acta Histochem.1997; 99: 301–309 /Bechakra, M. et al. Mol.Pain.2018; 14, 1744806918797040
English
Deutsch
