Clone Name: 7A1
Light Chain: Kappa
Application Note: WB: ~0.5 μg /ml. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Specificity/Sensitivity: We do not recommend use of this product for Mouse.
Form: Liquid
Buffer (with preservative): Filter-sterilized PBS, 50% Glycerol, no preservative.
Concentration: 1 mg/ml (Please refer to the vial label for the specific concentration.)
Background: The protein encoded by this gene is a membrane glycosylphosphatidylinositol-anchored glycoprotein that tends to aggregate into rod-like structures. The encoded protein contains a highly unstable region of five tandem octapeptide repeats. This gene is found on chromosome 20, approximately 20 kbp upstream of a gene which encodes a biochemically and structurally similar protein to the one encoded by this gene. Mutations in the repeat region as well as elsewhere in this gene have been associated with Creutzfeldt-Jakob disease, fatal familial insomnia, Gerstmann-Straussler disease, Huntington disease-like 1, and kuru. An overlapping open reading frame has been found for this gene that encodes a smaller, structurally unrelated protein, AltPrp. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2014]
Uniprot ID: P04156
Antigen Species: Human
Immunogen: Recombinant human PrP lacking GPI anchor expressed and purified from rabbit kidney cell line RK13
Purification: Purified IgG
Conjugation: Unconjugated
Full Name: prion protein
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