Abbreviation: Pro-glucagon
Target Synonym: GCG;GLP-1;GLP1;GLP2;GRPP;glucagon
Conjugation: Unconjugated
UNIProt ID: P01275
Background: The protein encoded by this gene is actually a preproprotein that is cleaved into four distinct mature peptides. One of these, glucagon, is a pancreatic hormone that counteracts the glucose-lowering action of insulin by stimulating glycogenolysis and gluconeogenesis. Glucagon is a ligand for a specific G-protein linked receptor whose signalling pathway controls cell proliferation. Two of the other peptides are secreted from gut endocrine cells and promote nutrient absorption through distinct mechanisms. Finally, the fourth peptide is similar to glicentin, an active enteroglucagon.
Concentration: 1mg/mL
Immunogen: Recombinant fusion protein of human Pro-glucagon
Dilution: WB 1:500-1:2000,IHC 1:50-1:200,IF 1:50-1:200
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