Calculated MW: 28
Specificity/Sensitivity: The antibody is specific for proBDNF, it does not crossreact with proNGF, proNT-3 or mature BDNF.
Form: Liquid
Buffer (with preservative): PBS pH 7.4, 1% BSA, 0.05% sodium azide.
Concentration: 0.8 mg/ml (Please refer to the vial label for the specific concentration.)
Background: This gene encodes a member of the nerve growth factor family of proteins. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature protein. Binding of this protein to its cognate receptor promotes neuronal survival in the adult brain. Expression of this gene is reduced in Alzheimer's, Parkinson's, and Huntington's disease patients. This gene may play a role in the regulation of the stress response and in the biology of mood disorders. [provided by RefSeq, Nov 2015]
Uniprot ID: P23560
Antigen Species: Human
Immunogen: Peptide (C)DEDQKVRPNEENNKDAD, corresponding to amino acid residues 72-88 of human BDNF (precursor) (Accession P23560). Pro-domain of the BDNF protein.
Purification: Purified by antigen-affinity chromatography
Conjugation: Unconjugated
Full Name: brain derived neurotrophic factor
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