Propargyl-PEG2-acid, CAS 1859379-85-3

Product Description: Propargyl-PEG2-acid is a non-cleavable 2 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Propargyl-PEG2-acid is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Propargyl-PEG2-acid is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

Applications: Cancer-programmed cell death

Formula: C8H12O4

References: [1]Sano K, et al. Short PEG-linkers improve the performance of targeted, activatable monoclonal antibody-indocyanine green optical imaging probes. Bioconjug Chem. 2013 May 15;24(5):811-6.

CAS Number: 1859379-85-3

Molecular Weight: 172.18

Compound Purity: 98.0

Research Area: Cancer

Solubility: DMSO : 250 mg/mL (ultrasonic)

Target: ADC Linker;PROTAC Linkers

• SKU: MEXHY-118764-100
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-118764-100
• Green Labware: No
• Package Unit: 100 mg
• Quantity Unit: STK