Prostaglandin I Synthase Monoclonal Antibody (Clone 3C8)

Formulation: 200 µg of lyophilized protein G-purified monoclonal antibody

Immunogen: Cell surface PGIS from follicular dendritic cell line HK

Clone Designation: 3C8

Shelf life (days): 1095

Notes: Prostaglandin I synthase (PGIS) catalyzes the isomerization of PGH2 to PGI2. PGI2 (prostacyclin) is a potent vasodilator and inhibitor of platelet aggregation. PGIS is a membrane-bound hemoprotein localized primarily in endothelial cells.{3476} The cloned bovine and human enzymes contain 500 amino acids and a calculated molecular mass of 56,629 and 57,103, respectively.{3477,3478,3475} Northern blot analysis reveals that the mRNA for PGIS is expressed in a wide variety of human tissues and is particularly abundant in ovary, heart, skeletal muscle, lung, and prostate.{3477}

• SKU: CAY10247-200
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 10247-200
• Green Labware: No
• Package Unit: 1 ea (200 µg)
• Quantity Unit: STK
• Clonality: Monoclonal
• Application: Immunoprecipitation, Western Blotting, Flow Cytometry, Immunohistochemistry, Immunocytochemistry
• Host: Mouse