PTDA-PEG4-azide, CAS 2639395-40-5

Product Description: PTAD-PEG4-N3 is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. PTAD-PEG4-N3 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

Applications: Cancer-programmed cell death

Formula: C22H33N7O9

References: [1]Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.

CAS Number: 2639395-40-5

Molecular Weight: 539.54

Compound Purity: 99.34

Research Area: Cancer

Solubility: DMSO : 125 mg/mL (ultrasonic)

Target: ADC Linker

• SKU: MEXHY-130940-50
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-130940-50
• Package Unit: 50 mg
• Quantity Unit: STK