Storage: Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.
Abbreviation: CD20/MS4A1
Target Synonym: LEU,CVID,B-lymphocyte antigen CD,Leukocyte surface antigen Leu,B-lymphocyte surface antigen B,Membrane-spanning 4-domains subfamily A member,MS4A1,B1,Bp35,CD20,CVID5,LEU-16,MS4A2,S7,B-lymphocyte antigen CD20,B-lymphocyte surface antigen B1,Leukocyte surface antigen Leu-16,Membrane-spanning 4-domains subfamily A member 1,Bp35,Ly-44,APY,ATOPY,B lymphocyte antigen CD20,B Lymphocyte Cell Surface Antigen B1,B-lymphocyte cell-surface antigen B1,Bp 35,CD 20,CD20 antigen,CD20 receptor,Fc epsilon receptor I beta chain,Fc Fragment of IgE high affinity I receptor for beta polypeptide,FCER1B,High affinity immunoglobulin epsilon receptor subunit beta,IgE Fc receptor subunit beta,IGEL,IGER,IGHER,LEU 16,LEU16,leukocyte surface antigen Leu 16,Ly44,Membrane spanning 4 domains A1,Membrane spanning 4 domains subfamily A member 2,MGC3969
Background: CD20 is a 297 amino acid (aa) non-glycosylated type III membrane protein that is the founding member of the MS4A tetraspanin protein family. It is expressed on pre-B, naïve and mature B lymphocytes and B-cell lymphomas. CD20 is associated with lipid rafts upon crosslinking, and appears to play a role in regulation of ion influx. The one extracellular segment of 48 aa shows 65% aa sequence identity between human and mouse CD20.
Immunogen: Recombinant Human CD20 protein
Buffer: PBS, pH 7.2. Contains 0.05% proclin 300.
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