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Clone Name: HL2758
Light Chain: Kappa
Application Note: WB: 1:500-1:3000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Calculated MW: 55
Specificity/Sensitivity: This antibody was raised against human PVRL4 Extracellular domain.
Form: Liquid
Buffer (with preservative): PBS, no Preservative.
Concentration: batch dependent (Please refer to the vial label for the specific concentration.)
Background: This gene encodes a member of the nectin family. The encoded protein contains two immunoglobulin-like (Ig-like) C2-type domains and one Ig-like V-type domain. It is involved in cell adhesion through trans-homophilic and -heterophilic interactions. It is a single-pass type I membrane protein. The soluble form is produced by proteolytic cleavage at the cell surface by the metalloproteinase ADAM17/TACE. The secreted form is found in both breast tumor cell lines and breast tumor patients. Mutations in this gene are the cause of ectodermal dysplasia-syndactyly syndrome type 1, an autosomal recessive disorder. Alternatively spliced transcript variants have been found but the full-length nature of the variant has not been determined.[provided by RefSeq, Jan 2011]
Uniprot ID: Q96NY8
Antigen Species: Human
Immunogen: Recombinant protein encompassing a sequence within the Extracellular domain of human PVRL4. The exact sequence is proprietary.
Purification: Affinity purified by Protein A.
Conjugation: Unconjugated
Full Name: nectin cell adhesion molecule 4
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