Rabbit anti-Bub1 Antibody, Affinity Purified

Stock Concentration: 1000 µg/ml

Conjugate Type: Unconjugated

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide

Shelf Life: 1 year from date of receipt

Protein ID: NP_004327.1

Uniprot ID: O43683

Background: Bub1 is cell cycle checkpoint kinase and component of the spindle checkpoint machinery. Bub1 and other spindle checkpoint proteins ensure that segregation does not proceed until all replicated chromatids are associated with a functional bipolar spindle. Bub1 functions to target Bub1-related protein (BubR1), Mad2, and polo-like kinase to kinetochores. It also functions to phosphorylate Cdc20 and inhibit ubiquitination of Pds1/securin by the anaphase-promoting complex (APC).

Immunogen: Between 1 and 50

• SKU: BEYA300-373A
• Manufacturer: Bethyl Laboratories
• Manufacturer SKU: A300-373A
• Green Labware: No
• Package Unit: 100 µl
• Quantity Unit: STK
• Reactivity: Human
• Clonality: Polyclonal
• Application: Immunoprecipitation, Western Blotting, Immunohistochemistry
• Isotype: Whole IgG
• Human Gene ID: 699
• Host: Rabbit