Rabbit anti-CDC20 IHC Antibody, Affinity Purified

Stock Concentration: 500 µg/ml

Conjugate Type: Unconjugated

Buffer: Tris-buffered Saline containing 0.1% BSA and 0.09% Sodium Azide

Shelf Life: 1 year from date of receipt

Protein ID: NP_001246.2

Uniprot ID: Q12834

Background: CDC20 is a WD repeat containing cell cycle-regulator that binds to and activates the ubiquitin-ligase activity of the APC/c (anaphase-promoting complex/cyclosome). APC/c ubiquitinating activity is responsible for the degradation of securin and cyclin B that prompts the onset of anaphase and exit from mitosis. CDC20 has also been reported to form a complex with histone deacetylases and can function as a transcriptional repressor involved in cell cycle arrest. As a regulator of APC/c activity, CDC20 plays a key role in the spindle-assembly checkpoint.

Immunogen: Between 50 and 100

• SKU: BEYIHC-00232
• Manufacturer: Bethyl Laboratories
• Manufacturer SKU: IHC-00232
• Package Unit: 100 µl
• Quantity Unit: STK
• Reactivity: Human, Mouse (Murine)
• Clonality: Polyclonal
• Application: Immunohistochemistry
• Isotype: Whole IgG
• Human Gene ID: 991
• Host: Rabbit
• Conjugate: Unconjugated