Rabbit anti-CHD1 Antibody, Affinity Purified

Stock Concentration: 1000 µg/ml

Conjugate Type: Unconjugated

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide

Shelf Life: 1 year from date of receipt

Protein ID: NP_001261.2

Uniprot ID: O14646

Background: CHD1 is a member of the CHD (chromodomain-helicase-DNA-binding) family of proteins that interacts with nucleosomes and plays a role in chromatin remodeling to modulate transcription. The members of the CHD family of proteins possess 3 common structural and functional domains: a chromodomain (chromatin organization modifier), an SNF2-like helicase/ATPase domain, and a C-terminal DNA-binding domain. CHD1 has been shown to interact with the transcriptional corepressor NCoR and histone deacetylase 1 indicating a role in transcriptional regulation. CHD1 has also been shown to interact with the Paf1 complex and Rtf1 implicating an additional role in transcriptional elongation.

Immunogen: Between 1500 and 1550

• SKU: BEYA301-217A-T
• Manufacturer: Bethyl Laboratories
• Manufacturer SKU: A301-217A-T
• Package Unit: 10 µl
• Quantity Unit: STK
• Reactivity: Human
• Clonality: Polyclonal
• Application: Immunoprecipitation
• Human Gene ID: 1105
• Host: Rabbit