Stock Concentration: 200 µg/ml
Conjugate Type: Unconjugated
Buffer: Tris-buffered Saline containing 0.1% BSA and 0.09% Sodium Azide
Shelf Life: 1 year from date of receipt
Protein ID: NP_060250.2
Uniprot ID: Q9P2D1
Background: CHD7 is a member of the CHD (chromodomain-helicase-DNA-binding) family of proteins that interacts with nucleosomes and plays a role in chromatin remodeling to modulate transcription. The members of the CHD family of proteins possess 3 common structural and functional domains: a chromodomain (chromatin organization modifier), an SNF2-like helicase/ATPase domain, and a C-terminal DNA-binding domain. CHD7 is implicated to play a role in development. Mutations in CHD7 are associated with CHARGE syndrome, a multi-symptom syndrome characterized by congenital anomalies and malformations of the heart, inner ear, retina, and palate.
Immunogen: Between 2947 and C-terminus
English
Deutsch
