Rabbit anti-DNA Ligase 1 Antibody, Affinity Purified

Stock Concentration: 1000 µg/ml

Conjugate Type: Unconjugated

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide

Shelf Life: 1 year from date of receipt

Protein ID: NP_000225.1

Uniprot ID: P18858

Background: DNA ligase 1 catalyzes the joining of double-stranded DNA ends during replication, recombination, and repair. Structurally, DNA ligase 1 is toroidal and encircles nicked DNA substrates. The 9-1-1 complex, a DNA damage checkpoint complex, has been reported to associate with DNA ligase 1 and stimulate ligase activity. Mutations in DNA ligase 1 result in immunodeficiency and increased sensitivity to DNA-damaging agents.

Immunogen: Between 200 and 250

• SKU: BEYA301-136A
• Manufacturer: Bethyl Laboratories
• Manufacturer SKU: A301-136A
• Green Labware: No
• Package Unit: 100 µl
• Quantity Unit: STK
• Reactivity: Human
• Clonality: Polyclonal
• Application: Immunoprecipitation, Immunohistochemistry
• Isotype: Whole IgG
• Human Gene ID: 3978
• Host: Rabbit