Stock Concentration: 1000 µg/ml
Conjugate Type: Unconjugated
Buffer: Borate Buffered Saline (BBS) pH 8.2 with 0.09% Sodium Azide, BSA-Free
Shelf Life: 1 year from date of receipt
Protein ID: NP_004458.3
Uniprot ID: Q08830
Background: Hepassocin, also known as Fibrinogen-like 1 (FGL1), is a member of the fibrinogen family whose members share a fibrinogen domain at their C-termini. However, it lacks the platelet-binding site, cross-linking region and thrombin-sensitive site which are necessary for fibrin clot formation. Hepassocin/FGL1 is secreted by hepatocytes and may play a role in the development of hepatocellular carcinomas. Hepassocin/FGL1 is an immune suppressive molecule that inhibits antigen-specific T-cell activation by acting as a major ligand of LAG3 [taken from NCBI Entrez Gene (Gene ID: 2267)].
Immunogen: Residues 18-312 (full length)
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