Background: Phospholipid-mediated signalling on neurons provokes diverse responses such as neurogenesis, pattern formation and neurite remodelling. A recently uncovered novel set of molecules in the mammalian brain, named plasticity-related genes (PRGs) mediate lipid phosphate phosphatase activity and provide evidence for their involvement in mechanisms of neuronal plasticity.
Positive Control: Human brain lysate (Cat. No. X1633C).
Immunogen: Synthetic peptide derived from the LPPRP2 protein.
Purification Method: Antigen Immunoaffiinity Purification.
Formulation: Provided as solution in phosphate buffered saline with 0.08% sodium azide.
References: [1] Strausberg R.L., et al Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.; Proc. Natl. Acad. Sci. U.S.A. 99:16899-16903(2002).
[2] Strausberg R.; Submitted (JUN-2001) to the EMBL/GenBank/DDBJ databases.
[3] Morris A.J., Sigal Y.J., McDermott M., Sciorra V.A.; Submitted (MAY-2003) to the EMBL/GenBank/DDBJ databases.
[4] Savaskan N.E., Brauer A.U., Nitsch R.; Molecular cloning and expression regulation of PRG-3, a new member of the plasticity-related gene family.; Eur. J. Neurosci. 19:212-220(2004).
UniProt: Q96GM1.
Caution: This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals.
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