Rabbit anti-PARC/H7-AP1 Antibody, Affinity Purified

Stock Concentration: 1000 µg/ml

Conjugate Type: Unconjugated

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide

Shelf Life: 1 year from date of receipt

Protein ID: NP_055904.1

Uniprot ID: Q8IWT3

Background: PARC is a member of the cullin family of proteins that act as scaffolds to bring together ubiquitin E3 ligases, E2 conjugating enzyme, and substrate proteins to mediate the ubiquitination of substrate proteins. PARC is highly homologous to and can form heterodimers with CUL7 (cullin 7). PARC/H7 interacts with p53 and was initially thought to have a role in the sequestration of p53 to the cytoplasm. Recent studies demonstrate that PARC may not influence p53 function or localization, but rather p53 may serve to regulate PARC/H7-AP1 function.

Immunogen: Between 900 and 950

• SKU: BEYA300-097A-T
• Manufacturer: Bethyl Laboratories
• Manufacturer SKU: A300-097A-T
• Green Labware: No
• Package Unit: 10 µl
• Quantity Unit: STK
• Reactivity: Human
• Clonality: Polyclonal
• Application: Immunoprecipitation, Western Blotting
• Isotype: Whole IgG
• Human Gene ID: 23113
• Host: Rabbit