Rabbit anti-PARP1 Recombinant Monoclonal Antibody (BLR182J)

Stock Concentration: 1000 µg/ml

Conjugate Type: Unconjugated

Buffer: Borate Buffered Saline (BBS) pH 8.2 with 0.09% Sodium Azide, BSA-Free

Shelf Life: 1 year from date of receipt

Protein ID: NP_001609.1

Uniprot ID: P09874

Background: PARP1 (Poly-ADP-ribose polymerase 1) is a member of PARP family of enzymes that transfer the ADP-D-ribosyl group of NAD(+) to an acceptor carboxyl group on proteins. PARP1 catalyzes the poly-ADP-ribosylation of histone and non-histone proteins in response to DNA damage. The over-activation of PARP-1 in response to DNA damage has been shown to promote cell and tissue injury. This observation has initiated research into the therapeutic potential of PARP1 inhibitors in the treatment of cancer, cardiovascular disease, and brain injury.

Immunogen: Between 775 and 825

• SKU: BEYA700-182CF
• Manufacturer: Bethyl Laboratories
• Manufacturer SKU: A700-182CF
• Package Unit: 100 µl
• Quantity Unit: STK
• Reactivity: Human, Mouse (Murine)
• Clonality: Recombinant
• Application: Western Blotting, Immunohistochemistry, Immunocytochemistry
• Isotype: Whole IgG
• Human Gene ID: 142
• Host: Rabbit
• Conjugate: Unconjugated