Rabbit anti-SHARP Antibody, Affinity Purified

Stock Concentration: 1000 µg/ml

Conjugate Type: Unconjugated

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide

Shelf Life: 1 year from date of receipt

Protein ID: NP_055816.2

Uniprot ID: Q96T58

Background: SHARP functions as a transcriptional repressor by interacting with proteins involved in deacetylation such as the NuRD (nucleosome remodeling) complex. SHARP can also repress transcription by interacting with corepressors such as SMRT/NCoR (silencing mediator for retinoid and thyroid receptors/nuclear receptor corepressor). SHARP is able to suppress transcription through the Notch/RBP-J signaling pathway by competing RBP-J binding with the intracellular domain of Notch.

Immunogen: Between 1350 and 1400

• SKU: BEYA301-119A
• Manufacturer: Bethyl Laboratories
• Manufacturer SKU: A301-119A
• Green Labware: No
• Package Unit: 100 µl
• Quantity Unit: STK
• Reactivity: Human
• Clonality: Polyclonal
• Application: Immunoprecipitation
• Isotype: Whole IgG
• Human Gene ID: 23013
• Host: Rabbit