Rabbit anti-YTHDF2 Recombinant Monoclonal Antibody (BLR297M)

Stock Concentration: 500 µg/ml

Conjugate Type: Unconjugated

Buffer: Phosphate Buffered Saline (PBS) with 0.1% BSA and 0.09% Sodium Azide

Shelf Life: 1 year from date of receipt

Protein ID: NP_057342.2

Uniprot ID: Q9Y5A9

Background: YTHDF2 is a member of the YTH-domain containing (YT521-B homology) superfamily which also contains YTHDF1 and YTHDF3. These proteins share a conserved C-terminal YTH domain that specifically interacts with N6-methyladenosine (m6A) modified RNA. The m6A modification is present at internal sites of mRNAs and some non-coding RNAs and plays an important role in mRNA splicing, processing, and stability. YTHDF2 binding appears to promote mRNA degradation, but has minimal effect on translation efficiency. [adapted from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q9Y5A9].

Immunogen: Between 300 and 350

• SKU: BEYA700-297-T
• Manufacturer: Bethyl Laboratories
• Manufacturer SKU: A700-297-T
• Package Unit: 20 µl (2 blots)
• Quantity Unit: STK
• Reactivity: Human, Mouse (Murine)
• Clonality: Monoclonal
• Application: Western Blotting, Flow Cytometry
• Isotype: Whole IgG
• Human Gene ID: 51441
• Host: Rabbit
• Conjugate: Unconjugated