Stock Concentration: 1000 µg/ml
Conjugate Type: Unconjugated
Buffer: Phosphate Buffered Saline (PBS) with 0.09% Sodium Azide, BSA-Free
Shelf Life: 1 year from date of receipt
Protein ID: NP_057342.2
Uniprot ID: Q9Y5A9
Background: YTHDF2 is a member of the YTH-domain containing (YT521-B homology) superfamily which also contains YTHDF1 and YTHDF3. These proteins share a conserved C-terminal YTH domain that specifically interacts with N6-methyladenosine (m6A) modified RNA. The m6A modification is present at internal sites of mRNAs and some non-coding RNAs and plays an important role in mRNA splicing, processing, and stability. YTHDF2 binding appears to promote mRNA degradation, but has minimal effect on translation efficiency. [adapted from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q9Y5A9].
Immunogen: Between 300 and 350
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