Application Note: WB: 1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Calculated MW: 56
Form: Liquid
Buffer (with preservative): PBS, 50% Glycerol, no preservative.
Concentration: 1 mg/ml (Please refer to the vial label for the specific concentration.)
Background: The protein encoded by this gene is highly similar to S. cerevisiae DNA damage repair protein Rad18. Yeast Rad18 functions through its interaction with Rad6, which is an ubiquitin-conjugating enzyme required for post-replication repair of damaged DNA. Similar to its yeast counterpart, this protein is able to interact with the human homolog of yeast Rad6 protein through a conserved ring-finger motif. Mutation of this motif results in defective replication of UV-damaged DNA and hypersensitivity to multiple mutagens. [provided by RefSeq, Jul 2008]
Uniprot ID: Q9NS91
Antigen Species: Human
Immunogen: GST-fusion protein containing 113 carboxyl terminal of human Rad18
Purification: Purified by antigen-affinity chromatography
Conjugation: Unconjugated
Full Name: RAD18 E3 ubiquitin protein ligase
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