Clone Name: AT14G8
Light Chain: Kappa
Application Note: WB: Recommended starting dilution is 1:500.. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Calculated MW: 23
Form: Liquid
Buffer (with preservative): PBS, 10% Glycerol, 0.02% Sodium azide.
Concentration: 1 mg/ml (Please refer to the vial label for the specific concentration.)
Background: This gene encodes a protein containing a death domain (DD) motif. This protein recruits caspase 2/ICH1 to the cell death signal transduction complex, which includes tumor necrosis factor receptor 1 (TNFR1A) and RIPK1/RIP kinase, and acts in promoting apoptosis. A mutation in this gene was associated with cognitive disability. A related pseudogene is found on chromosome 3. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016]
Uniprot ID: P78560
Antigen Species: Human
Immunogen: The clone AT14G8 is derived from hybridization of mouse F2 myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human CRADD protein.
Purification: Protein A Purified
Conjugation: Unconjugated
Full Name: CASP2 and RIPK1 domain containing adaptor with death domain
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