Rat anti Human IL-10

Rat anti Human IL-10, Monoclonal, IgG1, Clone: R.625

Clone: R.625.

Background: IL-10 inhibits the synthesis of a number of cytokines, including IFN-gamma, IL-2, IL-3, TNF and GM-CSF produced by activated macrophages and by helper T-cells. It defects in IL10 are a cause of susceptibility to Crohn disease (CD) [MIM:266600]. CD is a form of remitting inflammatory bowel disease (IBD). CD may involve any part of the gastrointestinal tract, but most frequently the terminal ileum and colon. Bowel inflammation is transmural and discontinuous. Crohn disease is commonly classified as autoimmune disease.

Purification Method: Protein A/G Chromatography.

UniProt: P22301.

Caution: This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals.

• SKU: EXAX1305M
• Manufacturer: Exalpha Biologicals Inc
• Manufacturer SKU: X1305M
• Green Labware: No
• Package Unit: 100 µg
• Quantity Unit: STK
• Reactivity: Human
• Clonality: Monoclonal
• Application: Immunofluorescence, Flow Cytometry
• Isotype: IgG1
• Host: Rat