RBFOX1 Polyclonal Antibody, Rabbit

Abbreviation: RBFOX1

Target Synonym: RBFOX1;2BP1;A2BP1;FOX-1;FOX1;HRNBP1

Conjugation: Unconjugated

UNIProt ID: Q9NWB1

Background: The Fox-1 family of RNA-binding proteins is evolutionarily conserved, and regulates tissue-specific alternative splicing in metazoa. Fox-1 recognizes a (U)GCAUG stretch in regulated exons or in flanking introns. The protein binds to the C-terminus of ataxin-2 and may contribute to the restricted pathology of spinocerebellar ataxia type 2 (SCA2). Ataxin-2 is the product of the SCA2 gene which causes familial neurodegenerative diseases. Fox-1 and ataxin-2 are both localized in the trans-Golgi network. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Concentration: 1mg/mL

Immunogen: Recombinant fusion protein of human RBFOX1

Dilution: WB 1:500-1:2000,IF 1:100-1:200

• SKU: ELSE-AB-92804-200
• Manufacturer: Elabscience Biotechnology
• Manufacturer SKU: ELA-E-AB-92804-200
• Green Labware: No
• Package Unit: 200 µl
• Quantity Unit: STK
• Reactivity: Human, Mouse (Murine), Rat (Rattus)
• Clonality: Polyclonal
• Application: Immunofluorescence, Western Blotting
• Isotype: IgG
• Host: Rabbit