Abbreviation: TGFBR1
Target Synonym: TGF beta Receptor I;AAT5;Activin A receptor type II like kinase 53kDa;Activin receptor like kinase 5;ACVRLK 4;ALK 5;LDS1A;MSSE;Serine/threonine-protein kinase receptor R4;SKR4;TbetaR-I;TGFR 1
Target Species: Bovine
Expression Host: E.coli
Fusion Tag: N-His
UNIProt ID: O46680
Background: On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for TGF-beta.
Sequence: Ile 143-Leu 330
Purity: > 95 % as determined by reducing SDS-PAGE.
Formulation: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Endotoxin: Please contact us for more information.
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