Recombinant Human ACTN4 protein(His tag)

Abbreviation: ACTN4

Target Synonym: Non-muscle alpha-actinin 4

Target Species: Human

Expression Host: E.coli

Fusion Tag: N-His & C-His

UNIProt ID: O43707

Background: F-actin cross-linking protein which is thought to anchor actin to a variety of intracellular structures. This is a bundling protein (Probable). Probably involved in vesicular trafficking via its association with the CART complex. The CART complex is necessary for efficient transferrin receptor recycling but not for EGFR degradation.Involved in tight junction assembly in epithelial cells probably through interaction with MICALL2. Links MICALL2 to the actin cytoskeleton and recruits it to the tight junctions.May also function as a transcriptional coactivator, stimulating transcription mediated by the nuclear hormone receptors PPARG and RARA.

Sequence: Met1-Lys300

Purity: > 90 % as determined by reducing SDS-PAGE.

Formulation: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.

Endotoxin: Please contact us for more information.

• SKU: ELSPDEH100103-100
• Manufacturer: Elabscience Biotechnology
• Manufacturer SKU: ELA-PDEH100103-100
• Green Labware: No
• Package Unit: 100 µg
• Quantity Unit: STK