Abbreviation: AGT
Target Synonym: Aangiotensinogen;Alpha 1 antiproteinase antitrypsin;Ang;Angiotensin I;Angiotensin-3;ANGT;ANHU;ANRT;AT-2;PAT;Serpin A8;SERPINA8
Target Species: Human
Expression Host: HEK293 Cells
Fusion Tag: C-His
UNIProt ID: P01019
Background: Angiotensinogen is involved in maintaining blood pressure and in the pathogenesis of essential hypertension and preeclampsia. Genetic variations in Angiotensinogen are associated with susceptibility to essential hypertension, and can cause renal tubular dysgenesis, a severe disorder of renal tubular development. Defects in the encoding gene have also been associated with non-familial structural atrial fibrillation, and inflammatory bowel disease.
Sequence: Met1-Glu476
Purity: > 95 % as determined by reducing SDS-PAGE.
Formulation: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Endotoxin: Please contact us for more information.
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