Recombinant Human BAG3 protein (GST tag)

Abbreviation: BAG3

Target Synonym: BAG-3;Bag3;BAG3

Target Species: Human

Expression Host: E.coli

Fusion Tag: N-GST

UNIProt ID: O95817

Background: Co-chaperone for HSP70 and HSC70 chaperone proteins. Acts as a nucleotide-exchange factor (NEF) promoting the release of ADP from the HSP70 and HSC70 proteins thereby triggering client/substrate protein release. Nucleotide release is mediated via its binding to the nucleotide-binding domain (NBD) of HSPA8/HSC70 where as the substrate release is mediated via its binding to the substrate-binding domain (SBD) of HSPA8/HSC70.

Sequence: Gly 421-Ala 498

Purity: > 95 % as determined by reducing SDS-PAGE.

Formulation: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.

Endotoxin: Please contact us for more information.

• SKU: ELSPDEH100171-20
• Manufacturer: Elabscience Biotechnology
• Manufacturer SKU: ELA-PDEH100171-20
• Green Labware: No
• Package Unit: 20 µg
• Quantity Unit: STK