Description: FGF-basic, a member of the FGF family comprising 23 known proteins, plays a pivotal role in prenatal development, postnatal growth, and tissue regeneration. It facilitates cellular proliferation and differentiation in various tissues. This growth factor is non-glycosylated and binds to heparin, and it is expressed in multiple organs and cell types including the brain, pituitary, kidney, retina, bone, testis, adrenal gland, liver, monocytes, epithelial cells, and endothelial cells. FGF-basic communicates through several receptors including FGFR 1b, 1c, 2c, 3c, and 4. Recombinant Human FGF-basic is a 17.2 kDa protein composed of 154 amino acid residues.
Expression System: E. coli
Molecular Weight: 17.2 kDa
Class: Recombinant
Endotoxin Concentration: <1 EU/µg
Activity: Determined by a cell proliferation assay using Balb/c 3T3 cells. The expected ED50 is ≤ 0.1 ng/ml, corresponding to a specific activity of ≥ 1 x 10^7 units/mg.
Form: Lyophilized
Contains: no preservative
Storage Conditions: -20°C
Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses
Caution: For Research Use Only. Not for use in diagnostic procedures.
Gene Symbol: FGF2
Protein ID: P09038
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