Abbreviation: CA199
Target Synonym: Galactoside 3(4)-L-fucosyltransferase;Blood group Lewis alpha-4-fucosyltransferase;Lewis FT;Fucosyltransferase 3;Fucosyltransferase III;FucT-III;FUT3;FT3B;LE
Target Species: Human
Expression Host: E.coli
Fusion Tag: N-His
UNIProt ID: P21217
Background: May catalyze alpha-1,3 and alpha-1,4 glycosidic linkages involved in the expression of Vim-2, Lewis A, Lewis B, sialyl Lewis X and Lewis X/SSEA-1 antigens. May be involved in blood group Lewis determination; Lewis-positive (Le+) individuals have an active enzyme while Lewis-negative (Le-) individuals have an inactive enzyme. Also acts on the corresponding 1,4-galactosyl derivative, forming 1,3-L-fucosyl links.
Activity: Immunogen(E-AB-40309)
Sequence: Val35-Thr361
Purity: > 80 % as determined by reducing SDS-PAGE.
Formulation: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Endotoxin: Please contact us for more information.