Recombinant Human CC16 protein (His tag)

Abbreviation: Uteroglobin;SCGB1A1

Target Synonym: Uteroglobin;Clara cell phospholipid-binding protein;CCPBP;Clara cells 10 kDa secretory protein;CC10;Secretoglobin family 1A member 1;Urinary protein 1;UP-1;UP1;Urine protein 1;SCGB1A1;CCSP;UGB

Target Species: Human

Expression Host: HEK293 Cells

Fusion Tag: C-His

UNIProt ID: P11684

Background: Uteroglobin is a small; non-glycosylated secreted protein of the secretoglobin superfamily. It is produced by the non-ciliated; non-mucous secretory cells that predominate in lung bronchioles (Clara cells); and other non-ciliated epithelia that communicate with the external environment. Expression is induced by steroid hormones such as estrogen; and enhanced by the non-steroid hormone prolactin. Human Uteroglobin cDNA encodes a 21 amino acid (aa) signal sequence and a 70 aa mature protein. The mature protein forms a disulfide-linked head-to-tail homodimer of 16 kDa. This homodimer is thought to form a binding pocket that binds hydrophobic ligands such as phospholipids; progesterone and retinols. Binding of fibronectin to Uteroglobin in the kidney is thought to protect against nephropathy; while binding of the lipocalin-1 receptor has been reported to suppress cancer cell motility and invasion.

Sequence: Glu22-Asn91

Purity: > 95 % as determined by reducing SDS-PAGE.

Formulation: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.

Endotoxin: Please contact us for more information.

• SKU: ELSPDMH100049-100
• Manufacturer: Elabscience Biotechnology
• Manufacturer SKU: ELA-PDMH100049-100
• Green Labware: No
• Package Unit: 100 µg
• Quantity Unit: STK