Abbreviation: Collagen α-1 Chain;COL3A1
Target Synonym: Collagen alpha-1(III) chain;CO3A1_HUMAN;CO3A1;PⅢCP
Target Species: Human
Expression Host: E.coli
Fusion Tag: N-His
UNIProt ID: p02461
Background: Collagen type III is found in most soft connective tissues, such as skin, lung, and the vascular system, often in association with type I collagen. It is a trimer of alpha 1(III) chains that are linked by interchain disulfide bonds. Defective collagen type III is a cause of Ehlers-Danlos syndrome types III and IV and arterial aneurisms (1). This recombinant mini pro-alpha 1(III) collagen consists of a triple-helical region of Gly-Xaa-Yaa repeats, a short non-helical region, and the C?terminal propeptide. The C?terminal propeptide can be removed by the procollagen C?proteinase (BMP-1).
Sequence: Asp 1222-Leu 1466
Purity: > 95 % as determined by reducing SDS-PAGE.
Formulation: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Endotoxin: Please contact us for more information.
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