Description: G-CSF serves as a hematopoietic growth factor, prompting the growth of dedicated progenitor cells into neutrophils and boosting the capabilities of mature end-cells. Its production is triggered by specific signals from various cells like macrophages, fibroblasts, endothelial cells, and bone marrow stroma. Clinically, G-CSF aids in speeding up hematopoietic recovery following bone marrow transplantation. Notably, both human and murine G-CSF show reactivity across species. The recombinant Human G-CSF is a 18.7 kDa protein comprising 174 amino acid residues.
Expression System: E. coli
Molecular Weight: 18.7 kDa
Class: Recombinant
Endotoxin Concentration: <1 EU/µg
Activity: Determined by its ability to stimulate the proliferation of mouse NFS-60 cells. The expected ED50 is ≤ 0.1 ng/ml, corresponding to a specific activity of ≥ 1 x 10^7 units/mg.
Form: Lyophilized
Contains: no preservative
Storage Conditions: -20°C
Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses
Caution: For Research Use Only. Not for use in diagnostic procedures.
Gene Symbol: CSF3
Protein ID: P09919
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