Target Synonym: Interleukin-8;IL-8;C-X-C Motif Chemokine 8;CXCL8;Emoctakin;Granulocyte Chemotactic Protein 1;GCP-1;Monocyte-Derived Neutrophil Chemotactic Factor;MDNCF;Monocyte-Derived Neutrophil-Activating Peptide;MONAP;Neutrophil-Activating Protein 1;NAP-1
Target Species: Human
Expression Host: HEK293 Cells
Fusion Tag: C-His
UNIProt ID: P10145
Background: Interleukin-8 (IL-8) belongs to the neutrophil-specific CXC family of chemokines. It is one of the initial cytokines released from a variety of cell types; including T cells; endothelial cells and fibroblasts; in response to an inflammatory stimulus and acts by recruiting neutrophils; T-cells and basophils to the site of inflammation. Elevated Interleukin-8 levels are associated with the onset of a variety of disease states.
Sequence: Glu21-Ser99
Purity: > 95 % as determined by reducing SDS-PAGE.
Formulation: Lyophilized from a 0.2 um filtered solution of 20mM PB, 150mM NaCl, pH 7.4. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual.
Endotoxin: < 1.0 EU per ug of the protein as determined by the LAL method.