Recombinant Human KLK2 protein (His tag)

Recombinant Human KLK2 protein (His tag)
SKU
ELSPDEH100290-100
Packaging Unit
100 µg
Manufacturer
Elabscience Biotechnology

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Abbreviation: KLK2

Target Synonym: Signal Transduction;Cell biology;Cancer

Target Species: Human

Expression Host: E.coli

Fusion Tag: N-His

UNIProt ID: P20151

Background: Kallikrein-2 (KLK2) is a secreted serine protease that belongs to the peptidase S1 family of Kallikrein subfamily. KLK2 contains 1 peptidase S1 domain. It is highly expressed in the human prostate gland. KLK2 can cleave Met-Lys and Arg-Ser bonds in kininogen to release Lys-bradykinin, but Preferential cleavages of Arg-|-Xaa bonds in small molecule substrates. It also highly selective action to release kallidin (lysyl-bradykinin) from kininogen involves hydrolysis of Met-|-Xaa or Leu-|-Xaa. KLK2 is inhibited by serpins such as protein C inhibitor, antichymotrypsin, and plasminogen. KLK2 is considered to be a biomarker for prostate cancer.

Sequence: Ile 25-Pro 261

Purity: > 95 % as determined by reducing SDS-PAGE.

Formulation: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.

Endotoxin: Please contact us for more information.
More Information
SKU ELSPDEH100290-100
Manufacturer Elabscience Biotechnology
Manufacturer SKU ELA-PDEH100290-100
Green Labware No
Package Unit 100 µg
Quantity Unit STK
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