Abbreviation: LILRB1
Target Synonym: Leukocyte Immunoglobulin-Like Receptor Subfamily B Member 1;LIR-1;Leukocyte Immunoglobulin-Like Receptor 1;CD85 Antigen-Like Family Member J;Immunoglobulin-Like Transcript 2;ILT-2;Monocyte/Macrophage Immunoglobulin-Like Receptor 7;MIR-7;CD85j;LILRB1;ILT2;LIR1;MIR7
Target Species: Human
Expression Host: HEK293 Cells
Fusion Tag: C-His
UNIProt ID: D9IDM8
Background: The immunoglobulin-like transcript (ILT) family (also named leukocyte Ig-like receptors (LIR) and monocyte/macrophage Ig-like receptors (MIR)) can be activating and inhibitory immunoreceptors. ILTs are expressed on many leukocyte subsets and regulators of immune responses . ILTs share significant homology with killer cell Ig-like receptors (KIR). Except ILT-6, all ILT family members are type I transmembrane proteins having two or four extracellular Ig-like domains . ILT2 is expressed on most monocytes,dendritic cells,and mature B cells. ILT2 is also expressed on small percentages of T-cells and NK cells. ILT2 can prevents cellular activation.
Sequence: Gly24-His458
Purity: > 95 % as determined by reducing SDS-PAGE.
Formulation: Lyophilized from a 0.2 um filtered solution of 20mM PB, 150mM NaCl, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Endotoxin: < 1.0 EU per ug of the protein as determined by the LAL method.
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